BVB330 Synthetic Genomics


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Unit Outline: Semester 2 2020, Gardens Point, Internal

Unit code:BVB330
Credit points:12
Pre-requisite:BVB317
Anti-requisite:BVB314, BVB327
Coordinator:Junior Te'o | junior.teo@qut.edu.au
Disclaimer - Offer of some units is subject to viability, and information in these Unit Outlines is subject to change prior to commencement of the teaching period.

Overview

With advances in DNA sequencing technologies, scientists are focusing more on analysing genomic DNA sequence information to explore and understand biological diversity and DNA modifications, improve agricultural practices, develop better drugs, and understand the genetic basis of disease. With the application of Recombinant gene technology and Synthetic biology, researchers can modify genes and genomes to create improved or better performing organisms to produce a target bioproduct, including whole cells, enzymes or metabolites. In this unit you will study fundamental and applied aspects of genome features, modifications and manipulation of genes and genomes and will be introduced to bioinformatic tools to analyse genomes for database mining, gene discovery and functional genomics. You will apply this knowledge to develop advanced data analysis skills, to carry out laboratory-based genetics and to edit and design synthetic genes and genomic pathways to solve biological problems.

Learning Outcomes

On successful completion of this unit you will be able to:

  1. Demonstrate knowledge in gene, peptide and genomic data analysis.
  2. Evaluate, critically analyse and interpret genetic and experimental data generated in laboratory classes.
  3. Demonstrate competence in solving biological problems through the application of analytical, critical thinking and problem solving skills.

Content

The content of this unit includes:

-Theoretical discussions about genomes
- Gene and biochemical pathway editing and expression analysis
- Different applications of genomes, genes and proteins/enzymes

Learning Approaches

This unit consists of a lecture/tutorial exercise and a analysis/laboratory session each week. The ideas presented in lectures and tutorials will be further developed and reinforced using hands-on analysis sessions, laboratory practical classes, interactive group work and a research project proposal.

Feedback on Learning and Assessment

Ongoing oral and written feedback will be provided throughout the semester on your performance in analytical and practical exercises. This feedback will help prepare you for the research proposal and end of semester examination.

Assessment

Overview

Assessment in this unit will consist of three elements:

  • Workshop practicals in genetic data analysis will be evaluated throughout the semester until week 12
  • An end of semester exam consisting of multiple choice, multiple answer and short essay questions
  • A scientific paper demonstrating critical thinking about a topic in genomics

Unit Grading Scheme

7- point scale

Assessment Tasks

Assessment: Laboratory/Practical

Practical: Progressive assessment based on the successful completion of problem-based learning practical exercises and laboratory classes. You are required to submit short reports on the learning modules throughout the semester and will be provided with prompt feedback.

 

Relates to learning outcomes
1, 2 and 3

Weight: 40
Individual/Group: Individual and group
Due (indicative): Weekly
Related Unit learning outcomes: 1, 2, 3

Assessment: Quiz

Late semester test consisting of ether multiple choice or True/False type questions.

 

Relates to learning outcomes
1 and 3

Weight: 20
Individual/Group: Individual
Due (indicative): Week 10
Related Unit learning outcomes: 1, 3

Assessment: Research Project Proposal

You will generate a research project proposal based on a problem solving task.  You will follow clear guidelines provided, and present your proposal in the form of a grant application, outlining clearly the topic, research problem, proposed solution, approach and expected outcomes.  

 

Relates to learning outcomes
1 and 3

Weight: 40
Individual/Group: Individual
Due (indicative): End of semester
Related Unit learning outcomes: 1, 3

Academic Integrity

Academic integrity is a commitment to undertaking academic work and assessment in a manner that is ethical, fair, honest, respectful and accountable.

The Academic Integrity Policy sets out the range of conduct that can be a failure to maintain the standards of academic integrity. This includes, cheating in exams, plagiarism, self-plagiarism, collusion and contract cheating. It also includes providing fraudulent or altered documentation in support of an academic concession application, for example an assignment extension or a deferred exam.

You are encouraged to make use of QUT’s learning support services, resources and tools to assure the academic integrity of your assessment. This includes the use of text matching software that may be available to assist with self-assessing your academic integrity as part of the assessment submission process.

Breaching QUT’s Academic Integrity Policy or engaging in conduct that may defeat or compromise the purpose of assessment can lead to a finding of student misconduct (Code of Conduct – Student) and result in the imposition of penalties under the Management of Student Misconduct Policy, ranging from a grade reduction to exclusion from QUT.

Resources

There is no set text but you will be provided with online resources and a current reading list.

Risk Assessment Statement

There are no out of the ordinary risks associated with this unit. You will be made aware of evacuation procedures and assembly areas in the first few lectures. In the event of a fire alarm sounding, or on a lecturer's instruction, you should leave the room and assemble in the designated area that will be indicated to you.